Eating less, if it is a high-quality diet, will improve your health, delay aging, and increase your chance of living a long, healthy and happy life. This is the first paper to show that long-term calorie restriction with optimal nutrition has cardiac-specific effects that ameliorate the age-associated decline in diastolic function in humans. In other words, this is the first report ever to show that calorie restriction with optimal nutrition may delay primary aging in human beings. Luigi Fontana